1) The base pairs in a DNA strand are held together with hydrogen bonds. If the two nitrogenous bases in each pair were held together with covalent bonds instead of hydrogen bonds, what effect would it have on the cell?
A) The cell could open and close the DNA strand with less effort if the bonds were covalent.
B) Each time the DNA strand opened the cell would need to replace the nitrogenous bases.
C) The cell would have to take in and use more energy in order to break the covalent bonds.
D) Since the covalent bonds are unbreakable it would be difficult for the cell to make mRNA.

2) How is the protein created from the mRNA sequence which reads AUGAUAGUGUAC different from the protein created from one that reads AUGAUAAGUUAC?
U

C

A

G

UUU

Phenylalanine

UCU

Serine

UAU

Tyrosine

UGU

Cysteine

U

U

UUC

Phenylalanine

UCC

Serine

UAC

Tyrosine

UGC

Cysteine

C

UUA

Leucine

UCA

Serine

UAA

Stop

UGA

Stop

A

UUG

Leucine

UCG

Serine

UAG

Stop

UGG

Tryptophan

G



CUU

Leucine

CCU

Proline

CAU

Hisitidine

CGU

Arginine

U

C

CUC

Leucine

CCC

Proline

CAC

Hisitidine

CGC

Arginine

C

CUA

Leucine

CCA

Proline

CAA

Glutamine

CGA

Arginine

A

CUG

Leucine

CCG

Proline

CAG

Glutamine

CGG

Arginine

G

AUU

Isoleucine

ACU

Threonine

AAU

Asparagine

AGU

Serine

U

A

AUC

Isoleucine

ACC

Threonine

AAC

Asparagine

AGC

Serine

C

AUA

Isoleucine

ACA

Threonine

AAA

Lysine

AGA

Arginine

A



AUG

Methionine/Start

ACG

Threonine

AAG

Lysine

AGG

Arginine

G

GUU

Valine

GCU

Alanine

GAU

Aspartate

GGU

Glycine

U

G

GUC

Valine

GCC

Alanine

GAC

Aspartate

GGC

Glycine

C



GUA

Valine

GCA

Alanine

GAA

Glutamate

GGA

Glycine

A

GUG

Valine

GCG

Alanine

GAG

Glutamate

GGG

Glycine

G

A) The first has fewer amino acids than the second.
B) The first has isoleucine where the second has leucine.
C) The first has one more amino acid than the second.
D) The first has valine while the second has serine.

3) Why do cells need both tRNA and mRNA?
A) Only mRNA can be used to repair mistakes in the DNA sequence.
B) Only tRNA bends into a shape that can carry specific amino acids.
C) The tRNA in used on the ribosomes and the mRNA is used in the nucleus.
D) The mRNA brings information to the nucleus for the tRNA to use.

4) Which of the following correctly describes the result of genetic mutations when they occur in a body cell?
A) The individual may have an advantage that is beneficial for survival.
B) The mutation will be passed on to the offspring in certain circumstances.
C) The individual will have an extra chromosome resulting from non-disjunction.
D) The mutation may affect the individual but will not be inherited by the offspring.

5) A chromosome that is exposed to a mutagen breaks into two pieces. A portion off one of the ends is removed before the two pieces rejoin. The mutation that occurs is
A) deletion
B) duplication
C) inversion
D) non-disjunction

6) Which of the following mutations is least likely to develop into a cancerous tumor?
A) A non-disjunction mutation
B) A chromosomal deletion mutation
C) A inversion chromosomal mutation
D) A single point mutation

7) Which of the following correctly explains how a mutation can result in a life-threatening cancer?
A) Cancer cells grow and destroy the blood supply to the area of the initial exposure.
B) Cancer cells cause an auto immune response which results in a build-up of cell matter.
C) Cancer cells invade and destroy healthy cells, disrupting their normal functions.
D) Cancer cells take over the function of healthy cells, avoiding detection by the immune system.

8) If a point mutation occurs in a body cell so that the original sequence of mRNA of CGA changes to AGA, what will be the likely consequence?
U

C

A

G

UUU

Phenylalanine

UCU

Serine

UAU

Tyrosine

UGU

Cysteine

U

U

UUC

Phenylalanine

UCC

Serine

UAC

Tyrosine

UGC

Cysteine

C

UUA

Leucine

UCA

Serine

UAA

Stop

UGA

Stop

A

UUG

Leucine

UCG

Serine

UAG

Stop

UGG

Tryptophan

G

UUU

Leucine

CCU

Proline

CAU

Hisitidine

CGU

Arginine

U

C

CUC

Leucine

CCC

Proline

CAC

Hisitidine

CGC

Arginine

C

CUA

Leucine

CCA

Proline

CAA

Glutamine

CGA

Arginine

A

CUG

Leucine

CCG

Proline

CAG

Glutamine

CGG

Arginine

G

AUU

Isoleucine

ACU

Threonine

AAU

Asparagine

AGU

Serine

U

A

AUC

Isoleucine

ACC

Threonine

AAC

Asparagine

AGC

Serine

C

AUA

Isoleucine

ACA

Threonine

AAA

Lysine

AGA

Arginine

A

AUG

Methionine/Start

ACG

Threonine

AAG

Lysine

AGG

Arginine

G

GUU

Valine

GCU

Alanine

GAU

Aspartate

GGU

Glycine

U

G

GUC

Valine

GCC

Alanine

GAC

Aspartate

GGC

Glycine

C

GUA

Valine

GCA

Alanine

GAA

Glutamate

GGA

Glycine

A

GUG

Valine

GCG

Alanine

GAG

Glutamate

GGG

Glycine

G

A) The mutation will cause a translocation to occur.
B) The mutation will cause a change in the individual but it will not be inherited.
C) The mutation will be inherited by the offspring.
D) The mutation will not cause any change in the individual and it will not be inherited.

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