The 5′ end of the DNA growing strand during DNA replicationA) is the part of the strand that is added last.B) does not contain a phosphate group on the ribose.C) is the part of the strand that is added first.D) is the end of both strands of DNA in a double helix.E) could contain the base uracil.

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Answer:

C) is the part of the strand that is added first

Explanation:

DNA replication occur by a semiconservative model. During DNA replication the strands of DNA are unbounded by DNA helicase and stabilized by single cell binding proteins.

The primase enzyme build the short primers and DNA polymerase synthesize the new strand of DNA. One restriction for DNA polymerase is that it can only synthesize the DNA strand in 5' to 3' direction. That's why 5' end of DNA is always synthesized first.

The leading strand is synthesized continuously and lagging strand is synthesized in fragments known as okazaki fragments because of DNA polymerase ability to synthesize the strand in only 5' to 3' direction. These fragments are joined by DNA ligase and RNA primers are also replaced by DNA polymerase.

At the time of the replication of DNA, the 5 prime end of the DNA strand is the part of the strand, which is added first.

What are the steps of DNA replication?

The replication of DNA takes place by a semiconservative model. At the time of the replication of DNA, the unbounding of the strands of DNA takes place with the help of enzyme helicase and is stabilized with the help of single cell binding proteins. The short primers are created by enzyme primase and the synthesis of novel strand of DNA takes place with the help of enzyme DNA polymerase.

The criteria for the working of DNA polymerase is that it can only synthesize the strand of DNA in 5 prime to 3 prime direction. This shows that the 5 prime end of the DNA is synthesized first. The synthesis of leading strand takes place spontaneously and synthesis of lagging strand takes place in fragments as Okazaki fragments with the tendency of DNA polymerase to produce the strand in 5 prime to 3 prime direction.

Thus, the correct answer is option C.

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